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| Directed by | |
|---|---|
 | Anne Fletcher |
| Starring | ||
|---|---|---|
 | Barbra Streisand | Joyce Brewster |
 | Seth Rogen | Andrew Brewster |
| Kathy Najimy | Gayle |
| Miriam Margolyes | Anita |
| Rose Abdoo | Diana |
| Tom Virtue | Mature Singles Man |
| Vivian Vanderwerd | Mature Singles Woman |
| Worth Howe | Bob |
| Vicki Goldsmith | Young Joyce |
| Matthew Levinson | Toddler Andy |
| Joseph Levinson | Toddler Andy |
| Kevin OKeefe | Budget Car Renter |
| Rick Gonzalez | Mark |
| Jeff Witzke | Middlesex Voice Over |
| Casey Wilson | Amanda |
| Steve Tom | OSH Executive |
| David Boller | Viriginia Hotel Clerk |
| Gabrielle Gumbs | Stripper |
| Dale Dickey | Tammy |
| Analeis Lorig | Moonlight |
| Yvonne Strahovski | Jessica |
 | Colin Hanks | Rob |
| Brandon Keener | Ryan Mcfee |
| Jeff Kober | Jimmy |
| Lorna Scott | Waitress |
| Kathleen Fletcher | Waitress |
| Kim Robillard | Emcee at Cattleman's Ranch |
| Brett Cullen | Ben Graw |
| Pedro Lopez | Hitchhiker |
| Jen Zaborowski | Caesar's Check-In Clerk |
| Fred Fletcher | Slots Player |
| Darryl Sivad | HSN Producer |
| Nora Dunn | Amy |
| Davis Neves | HSN Makeup Artist |
| Jackson Douglas | HSN Executive |
| Constance Esposito | HSN Executive |
| Adam Scott | Andrew Margolis, Jr. |
| Ari Graynor | Joyce Margolis |
| Patrick S. Harrigan | Man on Cell Phone |
| Shirley Claudia Charles | Frantic Mom |
| Dewain Robinson | Lost Son |
| James Barbour | Product Pitchman |
| Dave Bean | Suitor #2 |
| Yuki Bird | Traveler |
| Melanie Booth | Sarah |
| Creed Bratton | Suitor |
| Michael Cassidy | Fake Andy |
| Patty Chong | Asian Tour Guide |
| Roslyn Cohn | Costco Receptionist |
| Sheldon Coolman | Ashish |
| Sheena Crothers | Lisa's friend |
| Andy Dale | Camper |
| Shaun Daley | Pool Player |
| Ningning Deng | Hotel Clerk #1 |
| Timothy TJ James Driscoll | Retro Shirt Salesman |
| Mads Finegan-Smith | 10 yr old Young Andy |
| Joe Ford | Casino Gambler |
| Lubella Gauna | Restaurant Patron |
| Julian Graham | Daniel Bard |
| Brice Harris | Costco pitchman |
| Dallas James | Strip Club Patron |
| B. Johnson | Hotel Clerk #2 |
| Joy A. Kennelly | Business woman |
| David Dustin Kenyon | Park Ranger |
| Stephanie Masoner | Cocktail Server |
| Emily Pelz | Soccer Girl |
| Nataly Peña | Dancer |
| Craig Pollack | Bouncer |
| Danny Pudi | Sanjay |
| Alan D. Purwin | Helicopter Pilot |
| Mark Rowlett | Meteorologist on TV in Abilene Motel |
| Wilder Shaw | 18 Year-Old Andy |
| Eddie Shin | Chris Chung |
| Michael James Spall | Grand Canyon Motorcycle Rider |
| John H. Tobin | Hotel Guest |
| Amanda Walsh | Lisa |
| Patrick Weil | Airline Passenger |
| Anna Wendt | Lady at Limousine |
| Fritz Wurster | 14 year old Andy |
| Tawny Amber Young | Stripper |
| Julene Renée | K-Mart Receptionist |
| Zabryna Guevara | K-Mart Executive |
| John Funk | K-Mart Executive |
| Robert Curtis Brown | K-Mart Executive |
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Canada release date: 19th December 2012 USA release date: 19th December 2012 Australia release date: 24th January 2013
Brazil release date: 25th January 2013
Israel release date: 31st January 2013 Brazil United States
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